Poster Presentation 51st International Society for the Study of the Lumbar Spine Annual Meeting 2025

Ten-year trajectories of spine-specific activity limitations among patients with non-specific chronic low back pain (#178)

Viet-Thi TRAN 1 , Raphaël PORCHER 1 , Emmanuel COUDEYRE 2 , Camille DASTE 1 , Mathieu DE SEZE 3 , Arnaud DUPEYRON 4 , Marie-Martine LEFEVRE-COLAU 1 , Alexandra RÖREN 1 , François RANNOU 1 , Christelle NGUYEN 1
  1. Université Paris Cité, PARIS, ÎLE-DE-FRANCE, France
  2. Service de MPR, CHU Clermont-Ferrand, Clermont-Ferrand, France
  3. Service de MPR, CHU Bordeaux, Bordeaux, France
  4. Service de MPR, CHU Nîmes, Nîmes, France

INTRODUCTION

Long-term evolution of disability in patients with chronic low back pain has been scarcely modelized. We aimed to identify the 10-year trajectories of spine specific-activity limitations in patients with non-specific chronic low back pain.

 

METHODS

ComPaRe is an e-cohort of 50,000 participants with chronic diseases regularly monitored using patient-reported outcome measurements (PROMs) and patient-reported experience measurements (PREMs). Within ComPaRe, a specific sub-cohort of participants with non-specific chronic low back pain was launched in 2018 with follow-up every 4 months by the Roland Morris self-reported scale assessing spine-specific activity limitations. Using latent class mixed models, we modelized the trajectories of spine-specific activity limitations according to the Roland Morris score in participants with non-specific chronic low back pain, in the 10 years following low back pain onset.

 

RESULTS

Overall, 965 participants (18,996 person-months) were included in the analysis [74% female, median age 47.6, interquartile range (IQR) 37.4 to 56.8, median time since diagnosis 3.1 years, IQR 1.0 to 5.9]. Three trajectories of spine-specific activity limitations were identified: "high level of spine-specific activity limitations with persistence and/or worsening" (47%), "high level of spine-specific activity limitations with improvement" (33%) and "moderate level of spine-specific activity limitations with improvement" (20%). Participants with high level of spine-specific activity limitations with persistence and/or worsening more frequently reported comorbidities at the time of diagnosis including chronic fatigue, fibromyalgia, irritable bowel syndrome. Other groups of participants reported an improvement in their Roland Morris scale score of around 50% within 10 years.

 

DISCUSSION

Approximately 50% of participants with non-specific chronic low back pain will experience an improvement in spine-specific activity limitations over time. Others will experience significant and persistent spine-specific activity limitations.