Friday, 16th May 51st International Society for the Study of the Lumbar Spine Annual Meeting 2025

• Priming Human Nasal Chondrocytes for IVD Repair: Exploring Molecular Mechanisms of Survival and Inflammation Resistance - Günther Schäefer
• Distraction injures the spinal cord through the activation of sphingosine-1-phosphate receptor 2 - Yong Hai
• Contribution of Monocyte and Macrophage to Inflammatory Response and Pain Sensitization Following Disc Herniation - Xudong Li
• Freezing-Induced Interlamellar Mechanical Changes in Degenerated Annulus Fibrosus - Mohammed A Salaam
• Effect of Nucleus Pulposus Allograft on Intervertebral Disc Viscoelasticity and Dynamic Loading Response - Parto Babaniamansour
• Intradiscal Augmentation with Nucleus Pulposus Allograft for Symptomatic Discogenic Low Back Pain: A Prospective, Multi-center, Pilot Study. - Matthew C Shonnard

• Spine provider attitudes and beliefs on low back pain and opioid prescribing: A preliminary investigation - John Popovich
• Clinical Features of Interspinous Ligament Lesion in Adolescent Patients with Low Back Pain - Kenji Hatakeyama
• Demographic and Biomedical Characteristics of Individuals with Chronic Low Back Pain Enrolled in the LB3P Study - Meenakshi Sundaram
• The effect of spine-hip BMD discordance on treatment of osteoporosis in patients with osteoporotic vertebral compression fractures - Jun-Seok Lee
• A Mean 10-year Follow-up of Dynamic Stabilization Using Segmental Spinal Correction System - Masaru Tanaka
• Acceptance and commitment therapy plus exercise for older adults with chronic low back pain: a preliminary cluster randomized controlled trial with qualitative research - Arnold Wong

• DeVa (Decay Variance): A Novel Score Calculated via Postprocessing the Changes in Signal Intensity of an Intervertebral Disc in a T2* Multi-Echo Magnetic Resonance Image can Quantify Painful and Degenerate Lumbar Vertebral Discs - Stone Sima
• Prediction of Pathological Fractures in Spinal Metastases of Lung Cancer Using FDG-PET - Kosuke Takeda
• Load-induced alterations in posterior parts of intervertebral discs in patients with load-induced pain during MRI; a detailed study using T2 maps   - Helena Brisby
• Distinctive Features of Upright CT Myelography in Patients with Lumbar Spine Degenerative Diseases - Soya Kawabata
• Automatic generation of diffusion tensor imaging for the lumbar nerve using convolutional neural networks - Rira Masumoto
• Deep Learning-Based Object Detection Algorithm Using Magnetic Resonance Imaging for Differentiating Pathological Vertebral Fractures Caused by Malignant Metastatic Cancer in Patients with Vertebral Compression Fractures - Joonghyun Ahn

• Evaluation of Low Back Pain through Surface Electromyographic Analysis of Erector Spinae Muscles Across Various Postures - Takato Hoshino
• Asymmetrical thoracic and lumbar paraspinal muscle degeneration affects spinal curvature in an unexpected way - Aliza R. Siebenaller
• Introducing the Paraspinal Muscle Quality (PMQ) Score: A Novel T2-MRI Based Intensity Parameter for Assessing Spinal Sarcopenia - Ali Guven
• Transition and characteristics of adjacent disc vacuum phenomenon before and after balloon kyphoplasty - Hirohito Hirata
• Factors affecting postoperative recovery of lumbar lordosis after decompression surgery in patients with PI-LL mismatch - Akihiro Iida
• The Paraspinal Muscle Quality (PMQ) Score Predicts Frailty and Physical Performance in Spine Patients - Ali Guven

Three oral presentations will be followed by a 15-minute panel discussion.

• Adherence to exercise therapy and physical activity in non-specific chronic low back pain: a cross-sectional study of 491 individuals (ADHERE II) - Julien Giraudo
• Assessing Physical Activity in Chronic Low Back Pain: A Comparison of Wrist and Hip Worn Actigraph Sensors - Matthew Smuck
• Incidence of new onset leg pain following anterior approach lumbar surgery - Scott L Blumenthal
• Quantitative Sensory Testing in a Community Sample of Individuals with Chronic Low Back Pain - Gwendolyn Sowa
• Intradiscal STA363 in patients with radiculopathy caused by lumbar disc herniation produces volume reduction consistent with symptomatic relief - Matthew Shonnard
• Painful symptoms and spine-specific activity limitations associated with dural ectasia in individuals with Marfan syndrome: a cross-sectional comparative study (MARFANLOMB) - Sébastien TROUSSIER

Three oral presentations will be followed by a 15-minute panel discussion.

• Facet Joint Morphology and Scoliosis Progression in Lenke 1 AIS :Quantifying Inferior Articular Process Resection Width - Masaya Mizutani
• Modic changes associate with gut microbial dysbiosis - Jiamin Zhou
• The effect of unloaded rest and time of day on MRI measurements of disc T2 time and height   - Mackenzie N Conner
• Evaluation of Trunk muscles in lumbar degenerative disease using Magnetic Resonance Imaging T2 mapping: Association with Computed Tomography parameters, body composition, and clinical outcomes - Noritaka Suzuki
• Effective disc age: a statistical model for age-dependent and level-specific lumbar disc degeneration using magnetic resonance imaging (MRI) - Dawn M Elliott
• The Cross-Sectional Relationship between Gut Microbiome, Pain, and Disability in Chronic Low Back Pain. - Valerio Tonelli Enrico

Three oral presentations will be followed by a 15-minute panel discussion.

• Data-driven trajectories of lumbar spine degeneration in the comeBACK dataset - Terence McSweeney
• Risk factors for insufficient segmental lordosis following posterior lumbar interbody fusion: effect of change in segmental lordosis in the intraoperative prone position - Hiroyuki Ishiguro
• Surgical outcome of drop foot caused by degenerative lumbar disorders - prediction using calf circumference differences - Hiroyuki Aono
• Changes in sagittal alignment following lumbar total disc replacement: analysis based on full-body EOS imaging of 132 patients - Richard D Guyer
• Sex Specific Analysis of the Prognostic Factors Associated with Reaching Minimally Clinically Important Difference One-Year Post Surgery Across Common Degenerative Lumbar Conditions: A CSORN Study - Y. Raja Rampersaud