Friday, 16th May 51st International Society for the Study of the Lumbar Spine Annual Meeting 2025

• Priming Human Nasal Chondrocytes for IVD Repair: Exploring Molecular Mechanisms of Survival and Inflammation Resistance - Günther Schäefer
• Distraction injures the spinal cord through the activation of sphingosine-1-phosphate receptor 2 - Yong Hai
• Contribution of Monocyte and Macrophage to Inflammatory Response and Pain Sensitization Following Disc Herniation - Xudong Li
• Freezing-Induced Interlamellar Mechanical Changes in Degenerated Annulus Fibrosus - Mohammed A Salaam
• Effect of Nucleus Pulposus Allograft on Intervertebral Disc Viscoelasticity and Dynamic Loading Response - Parto Babaniamansour
• Intradiscal Augmentation with Nucleus Pulposus Allograft for Symptomatic Discogenic Low Back Pain: A Prospective, Multi-center, Pilot Study. - Matthew C Shonnard

• Spine provider attitudes and beliefs on low back pain and opioid prescribing: A preliminary investigation - John Popovich
• Clinical Features of Interspinous Ligament Lesion in Adolescent Patients with Low Back Pain - Kenji Hatakeyama
• Demographic and Biomedical Characteristics of Individuals with Chronic Low Back Pain Enrolled in the LB3P Study - Meenakshi Sundaram
• Feasibility and effectiveness of real-time biofeedback for maintaining lumbar lordotic curvature using inertial measurement system - Sun Gun Chung
• Acceptance and commitment therapy plus exercise for older adults with chronic low back pain: a preliminary cluster randomized controlled trial with qualitative research - Arnold Wong

• DeVa (Decay Variance): A Novel Score Calculated via Postprocessing the Changes in Signal Intensity of an Intervertebral Disc in a T2* Multi-Echo Magnetic Resonance Image can Quantify Painful and Degenerate Lumbar Vertebral Discs - Stone Sima
• Load-induced alterations in posterior parts of intervertebral discs in patients with load-induced pain during MRI; a detailed study using T2 maps   - Helena Brisby
• Distinctive Features of Upright CT Myelography in Patients with Lumbar Spine Degenerative Diseases - Soya Kawabata
• Automatic generation of diffusion tensor imaging for the lumbar nerve using convolutional neural networks - Rira Masumoto
• MIS-TLIF under O-arm navigation avoids violation of the supradjacent facet joint and delays its degeneration - Xu Sun

• Comparative Outcomes of Laminectomy with Arthrodesis versus sole Laminectomy in the Treatment of Single-Level Lumbar Listhesis: A Retrospective Study of 45 Cases - Ghassen Gader
• Does bone marrow edema on early postoperative MRI predict unsuccessful healing of interbody fusion? - Yukitoshi Shimamura
• Factors affecting postoperative recovery of lumbar lordosis after decompression surgery in patients with PI-LL mismatch - Akihiro Iida
• Do all symptomatic Adjacent Segment Diseases (ASD) require surgery? A Prognostic Classification and Predictors of Surgical treatment of Lumbar ASD - Rishi Kanna
• A Mean 10-year Follow-up of Dynamic Stabilization Using Segmental Spinal Correction System - Masaru Tanaka
• The impact of overall lumbar disc degeneration burden on disability outcomes following surgery for lumbar spinal stenosis due to osteoarthritis - Y. Raja Rampersaud

• Evaluation of Low Back Pain through Surface Electromyographic Analysis of Erector Spinae Muscles Across Various Postures - Takato Hoshino
• Asymmetrical thoracic and lumbar paraspinal muscle degeneration affects spinal curvature in an unexpected way - Aliza R. Siebenaller
• Introducing the Paraspinal Muscle Quality (PMQ) Score: A Novel T2-MRI Based Intensity Parameter for Assessing Spinal Sarcopenia - Ali Guven
• Machine Learning Integration of Structural Magnetic Resonance Imaging and Metabolomic Biomarkers for Early Detection of Lumbar Spondylosis - Rifaldy Fajar
• MRI-based vertebral bone quality score combined with fat infiltration of paraspinal muscles predicts adjacent segment degeneration following transforaminal lumbar interbody fusion  - Xu Sun
• The Paraspinal Muscle Quality (PMQ) Score Predicts Frailty and Physical Performance in Spine Patients - Ali Guven

Three oral presentations will be followed by a 15-minute panel discussion.

• Adherence to exercise therapy and physical activity in non-specific chronic low back pain: a cross-sectional study of 491 individuals (ADHERE II) - Christelle Nguyen
• Assessing Physical Activity in Chronic Low Back Pain: A Comparison of Wrist and Hip Worn Actigraph Sensors - Matthew Smuck
• A 10-year prognosis in patients with lumbar disc herniation treated with condoliase in a Japanese phase III trial - Kazuhiro Chiba
• Quantitative Sensory Testing in a Community Sample of Individuals with Chronic Low Back Pain - Gwendolyn Sowa
• Intradiscal STA363 in patients with radiculopathy caused by lumbar disc herniation produces volume reduction consistent with symptomatic relief - Matthew Shonnard
• Painful symptoms and spine-specific activity limitations associated with dural ectasia in individuals with Marfan syndrome: a cross-sectional comparative study (MARFANLOMB) - Christelle Nguyen

Three oral presentations will be followed by a 15-minute panel discussion.

• Resting-state EEG in females with or without chronic low back pain and comorbid insomnia - Jeremy Chang
• Modic changes associate with gut microbial dysbiosis - Jiamin Zhou
• The effect of unloaded rest and time of day on MRI measurements of disc T2 time and height   - Mackenzie N Conner
• Evaluation of Trunk muscles in lumbar degenerative disease using Magnetic Resonance Imaging T2 mapping: Association with Computed Tomography parameters, body composition, and clinical outcomes - Noritaka Suzuki
• Effective disc age: a statistical model for age-dependent and level-specific lumbar disc degeneration using magnetic resonance imaging (MRI) - Dawn M Elliott
• The Cross-Sectional Relationship between Gut Microbiome, Pain, and Disability in Chronic Low Back Pain. - Valerio Tonelli Enrico

Three oral presentations will be followed by a 15-minute panel discussion.

• Data-driven trajectories of lumbar spine degeneration in the comeBACK dataset - Terence McSweeney
• Recurrence of kyphosis after surgical fixation of burst fractures - Henrik Baecker
• Risk factors for insufficient segmental lordosis following posterior lumbar interbody fusion: effect of change in segmental lordosis in the intraoperative prone position - Hiroyuki Ishiguro
• Surgical outcome of drop foot caused by degenerative lumbar disorders - prediction using calf circumference differences - Hiroyuki Aono
• Changes in sagittal alignment following lumbar total disc replacement: analysis based on full-body EOS imaging of 132 patients - Emily C Courtois
• Sex Specific Analysis of the Prognostic Factors Associated with Reaching Minimally Clinically Important Difference One-Year Post Surgery Across Common Degenerative Lumbar Conditions: A CSORN Study - Y. Raja Rampersaud